Developing innovative 3D multi-cellular co-culture models to investigate the metabolic cross-talk between pancreatic cancer cells and the tumor microenvironment, aiming to identify novel therapeutic approaches for this disease.
Dr. Saranya Pounraj
Post-doctoral Researcher
PhD in Biological Sciences, Griffith University (2023)
Dr. Saranya Pounraj completed her Ph.D. in Biological Sciences in December 2023 at Griffith University, Queensland, where her research focused on developing personalized cancer vaccines from bacterial biopolymers. In January 2024, she began her post-doctoral career at the University of New South Wales (ÁñÁ«¹ÙÍø) in the Tumour Microenvironment group led by Dr. Kovacevic within the School of Biomedical Sciences. Her current research involves developing innovative 3D multi-cellular co-culture models to investigate the metabolic cross-talk between pancreatic cancer cells and the tumor microenvironment, aiming to identify novel therapeutic approaches for this disease.
Dr. Pounraj has published seven research articles in Q1 journals, garnering a total of 196 citations. Her h-index and i10-index are both 4 as of 2024, reflecting her significant contributions to the research field as an early career researcher.
Research focus
- Publications
- Research work
- Saranya Pounraj; Shuxiong Chen; Linlin Ma; Alfred Lam, Bernd H. A. Rehm " Engineering neoantigens to form immunogenic biopolymer particles targeting metastatic breast cancer. " Applied Materials Today, 38, 102238. (Impact Factor: 7.2). Q1
- Saranya Pounraj; Shuxiong Chen; Linlin Ma; Roberta Mazzieri and Riccardo Dolcetti, Bernd H.A. Rehm " Neoantigen-based cancer vaccines targeting tumor heterogeneity." Cancer Research (2024):1131057. (Impact Factor: 12.5). Q1
- Devi Jenika, Saranya Pounraj, David Wibowo, Leonhard M. Flaxl, Bernd H.A. Rehm Justine D. Mintern "In Vivo Assembly of epitope-coated biopolymer particles that induce anti-tumor responses.npj Vaccines (2022): 1131057. (Impact Factor: 9.2). Q1
- Chen, Shuxiong, Saranya Pounraj, Nivethika Sivakumaran, Anjali Kakkanat, Gayathri Sam, Md Tanvir Kabir, and Bernd HA Rehm "Precision-engineering of subunit vaccine particles for prevention of infectious diseases." Frontiers in Immunology (2023): 1131057. (Impact Factor: 9.8). Q1
- Saranya Pounraj, Tanmayee Bhilwadikar, Selladurai Manivannan, Navin K. Rastogi, and Pradeep S. Negi. "Effect of ozone, lactic acid and combination treatments on the control of microbial and pesticide contaminants of fresh vegetables." Journal of the Science of Food and Agriculture (2020). (Impact Factor: 4.1). Q1
- Bhilwadikar, Tanmayee, Saranya Pounraj, S. Manivannan, N. K. Rastogi, and P. S. Negi. "Decontamination of Microorganisms and Pesticides from Fresh Fruits and Vegetables: A Comprehensive Review from Common Household Processes to Modern Techniques." Comprehensive Reviews in Food Science and Food Safety 18, no. 4 (2019): 1003-1038. (Impact Factor: 14.8). Q1
- Saranya Pounraj, Prathap Somu, and Subhankar Paul. "Chitosan and graphene oxide hybrid nanocomposite film doped with silver nanoparticles efficiently prevents biofouling." Applied Surface Science 452 (2018): 487-497. (Impact Factor: 7.39). Q1
Figure: Effect of a high-potency drug on a co-culture model of pancreatic cancer cells and fibroblasts, demonstrating inhibition of metabolic cross-talk within the tumor microenvironment.